Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | FPR1 | P21462 | 7/20 | 0.39 |
| ▸ | FPR2 | P25090 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 4/20 | 0.37 |
| ▸ | NPY1R | P25929 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9105848 | 0.94 | GHSR (0.46) | GHSRAGTR1FPR1FPR2TSHR | |
| SCHEMBL9104494 | 0.93 | GHSR (0.49) | GHSRAGTR1TSHRMAPK1XIAP | |
| SCHEMBL9107007 | 0.92 | GHSR (0.59) | GHSRAGTR1FPR1FPR2XIAP | |
| SCHEMBL9105520 | 0.92 | GHSR (0.57) | GHSRAGTR1TSHRMAPK1XIAP | |
| SCHEMBL9107838 | 0.89 | GHSR (0.41) | GHSRAGTR1FPR1FPR2TSHR | |
| SCHEMBL7785974 | 0.87 | GHSR (0.56) | GHSRAGTR1FPR1FPR2XIAP | |
| SCHEMBL9107203 | 0.87 | GHSR (0.58) | GHSRAGTR1FPR1FPR2XIAP | |
| SCHEMBL9120688 | 0.87 | GHSR (0.46) | GHSRAGTR1FPR1FPR2XIAP | |
| SCHEMBL9120693 | 0.87 | GHSR (0.46) | GHSRAGTR1FPR1FPR2XIAP | |
| SCHEMBL9108609 | 0.87 | GHSR (0.58) | GHSRAGTR1FPR1FPR2XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430144-A | E.g, N-(1-((2'-((methoxycarbonyl)amino)(1,1'-biphenyl)-4-yl) methyl)-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-3-yl)-3 ((fur-2-yl)methyl)amino-3-methylbutanamide | MERCK & CO., INC. (US) | 1995-07-04 | — | — | US | disclosed |