SCHEMBL9106744

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9106736	1.00	TSHR (0.52)	TSHRHDAC1HDAC6HDAC8HDAC5
	SCHEMBL9103636	0.89	P2RX7 (0.47)	TSHRP2RX7CNR2MEN1KMT2A
	SCHEMBL9107374	0.89	TSHR (0.42)	TSHRHDAC1HDAC6HDAC8HDAC5
	SCHEMBL9108816	0.89	P2RX7 (0.47)	TSHRHDAC1HDAC6HDAC8HDAC5
	SCHEMBL9107363	0.89	TSHR (0.42)	TSHRHDAC1HDAC6HDAC8HDAC5
	SCHEMBL13285326	0.89	TSHR (0.45)	TSHRHDAC1HDAC6HDAC8HDAC5
	SCHEMBL9108825	0.89	P2RX7 (0.47)	TSHRHDAC1HDAC6HDAC8HDAC5
	SCHEMBL9109207	0.89	CCR1 (0.47)	TSHRHDAC1HDAC6HDAC8HDAC5
	SCHEMBL9109215	0.89	CCR1 (0.47)	TSHRHDAC1HDAC6HDAC8HDAC5
	SCHEMBL9103625	0.89	P2RX7 (0.47)	TSHRP2RX7CNR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.