Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106833 | 0.91 | PRSS1 (0.33) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL1295951 | 0.83 | TSHR (0.41) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL1296903 | 0.79 | TSHR (0.42) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL1297244 | 0.78 | ZDHHC7 (0.40) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL1297164 | 0.78 | PRSS1 (0.38) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL1297312 | 0.78 | PRSS1 (0.38) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL1297655 | 0.78 | PPM1B (0.38) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL1297743 | 0.78 | CYP3A4 (0.51) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL1297436 | 0.78 | NAAA (0.40) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL1298128 | 0.78 | PRSS1 (0.38) | PRSS1PRSS2PRSS3TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120138206-A1 | ADHESIVES AND SEALANTS CONTAINING CYCLOHEXANE POLYCARBOXYLIC ACID DERIVATIVES | BASF SE (DE) | 2012-06-07 | — | — | US | disclosed |