Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 4/20 | 0.49 |
| ▸ | GSK3B | P49841 | 4/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | CTRC | Q99895 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619566 | 0.81 | GSK3A (0.46) | GSK3AGSK3BDDB1CRBNKMT2A | |
| SCHEMBL7747497 | 0.74 | DDB1 (0.56) | GSK3AGSK3BDDB1CRBNKMT2A | |
| SCHEMBL5251522 | 0.71 | MAPT (0.70) | GSK3AGSK3BDDB1CRBNKMT2A | |
| SCHEMBL152680 | 0.71 | MAPT (0.70) | GSK3AGSK3BDDB1CRBNKMT2A | |
| SCHEMBL3313053 | 0.69 | L3MBTL1 (0.50) | GSK3AGSK3BDDB1CRBNKMT2A | |
| SCHEMBL19521066 | 0.68 | ELANE (0.44) | GSK3AGSK3BDDB1CRBNKMT2A | |
| SCHEMBL2122408 | 0.68 | GSK3A (0.51) | GSK3AGSK3BDDB1CRBNKMT2A | |
| SCHEMBL7741931 | 0.67 | MEN1 (0.55) | GSK3AGSK3BDDB1CRBNKMT2A | |
| SCHEMBL16416392 | 0.67 | KMT2A (0.76) | DDB1CRBNKMT2AMEN1F2 | |
| SCHEMBL1488276 | 0.67 | L3MBTL1 (0.56) | GSK3AGSK3BDDB1CRBNKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578761-A4 | ENZYMATIC PROCESS FOR THE PRODUCTION OF CEFONICID. | SMITHKLINE BEECHAM CORP (US) | 1995-08-09 | — | — | EP | disclosed |
| EP-0578761-A1 | ENZYMATIC PROCESS FOR THE PRODUCTION OF CEFONICID | SMITHKLINE BEECHAM CORPORATION (US) | 1994-01-19 | — | — | EP | disclosed |
| WO-1992017600-A1 | ENZYMATIC PROCESS FOR THE PRODUCTION OF CEFONICID | SMITHKLINE BEECHAM CORPORATION (US) | 1992-10-15 | — | — | WO | disclosed |
| EP-0243924-A2 | 2-Oxo-1-(substituted phosphorous)azetidines | E.R. Squibb & Sons, Inc. (US) | 1987-11-04 | — | — | EP | disclosed |
| EP-0200159-A2 | 3-Acylamino-2-oxo-1-azetidinesulfonic acids | E.R. Squibb & Sons, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |
| EP-0177940-A2 | Hydrazine derivatives and their use | E.R. Squibb & Sons, Inc. (US) | 1986-04-16 | — | — | EP | disclosed |
| EP-0138407-A1 | Azetidinones | E.R. Squibb & Sons, Inc. (US) | 1985-04-24 | — | — | EP | disclosed |
| EP-0135814-A1 | 1-(1H-tetrazol-5-ylalkoxy)-2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1985-04-03 | — | — | EP | disclosed |
| EP-0085291-A1 | 2-Oxo-1-(aminocarbonylaminosulfonylaminocarbonyl)azetidines | E.R. Squibb & Sons, Inc. (US) | 1983-08-10 | — | — | EP | disclosed |