Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9104960 | 0.88 | MAPT (0.49) | MAPTALOX15TDP1RAD52CYP3A4 | |
| SCHEMBL9105620 | 0.87 | MAPT (0.45) | MAPTALOX15TDP1RAD52CYP3A4 | |
| SCHEMBL9104049 | 0.85 | MAPT (0.48) | MAPTALOX15TDP1RAD52CYP3A4 | |
| SCHEMBL9104151 | 0.82 | MAPT (0.58) | MAPTALOX15TDP1RAD52CYP3A4 | |
| SCHEMBL9099987 | 0.82 | MAPT (0.39) | MAPTALOX15TDP1RAD52CYP3A4 | |
| SCHEMBL9101001 | 0.77 | MAPT (0.39) | MAPTALOX15TDP1RAD52CYP3A4 | |
| SCHEMBL9102418 | 0.77 | MAPT (0.53) | MAPTALOX15TDP1RAD52CYP3A4 | |
| SCHEMBL9103799 | 0.77 | POLB (0.42) | MAPTCYP3A4TP53POLBTSHR | |
| SCHEMBL9105518 | 0.75 | MEN1 (0.52) | MAPTALOX15TDP1RAD52CYP3A4 | |
| SCHEMBL9102093 | 0.74 | MAPT (0.49) | MAPTALOX15TDP1RAD52CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |