Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 9/20 | 0.34 |
| ▸ | NPY1R | P25929 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9105861 | 0.91 | GHSR (0.58) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL9109512 | 0.89 | GHSR (0.49) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL9024318 | 0.87 | GHSR (0.62) | GHSRAGTR1XIAPNPY1RCHRM1 | |
| SCHEMBL9025202 | 0.87 | GHSR (0.62) | GHSRAGTR1XIAPNPY1RCHRM1 | |
| SCHEMBL9106202 | 0.86 | GHSR (0.48) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL9107917 | 0.86 | GHSR (0.45) | GHSRAGTR1XIAP | |
| SCHEMBL9104201 | 0.85 | GHSR (0.48) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL9108578 | 0.85 | GHSR (0.48) | GHSRAGTR1XIAPNPY1R | |
| SCHEMBL9107656 | 0.84 | GHSR (0.41) | GHSRAGTR1XIAP | |
| SCHEMBL9108338 | 0.82 | GHSR (0.56) | GHSRAGTR1XIAPNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003290-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-02-02 | — | — | WO | claimed |
| US-5430144-A | E.g, N-(1-((2'-((methoxycarbonyl)amino)(1,1'-biphenyl)-4-yl) methyl)-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-3-yl)-3 ((fur-2-yl)methyl)amino-3-methylbutanamide | MERCK & CO., INC. (US) | 1995-07-04 | — | — | US | disclosed |