SCHEMBL9108224

SCHEMBL9108224

CCCCCCCCCCCCCCCCCCCc1ccccn1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.67
KCNH2 Q12809 1/20 0.62
NAAA Q02083 1/20 0.56
HRH3 Q9Y5N1 2/20 0.53
LMNA P02545 3/20 0.52
ALOX15 P16050 2/20 0.52
ALDH1A1 P00352 2/20 0.52
TAAR1 Q96RJ0 1/20 0.52
CYP1A2 P05177 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
CYP2C19 P33261 2/20 0.49
CYP19A1 P11511 3/20 0.47
HRH4 Q9H3N8 1/20 0.47
KDM4E B2RXH2 2/20 0.46
USP2 O75604 1/20 0.46
ALOX12 P18054 1/20 0.46
HTT P42858 1/20 0.46
NPC1 O15118 1/20 0.46
HSP90AA1 P07900 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3672276 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL666135 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL9572197 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL919951 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL25380743 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL180805 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL25381489 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL920310 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL21511268 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL5138374 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8926812-B2 Cell-based transparent sensor capable of real-time optical observation of cell behavior, method for manufacturing the same and multi-detection sensor chip using the same Research & Business Foundation Sungkyunkwan University (KR) 2015-01-06 US claimed
US-20120138458-A1 CELL-BASED TRANSPARENT SENSOR CAPABLE OF REAL-TIME OPTICAL OBSERVATION OF CELL BEHAVIOR, METHOD FOR MANUFACTURING THE SAME AND MULTI-DETECTION SENSOR CHIP USING THE SAME Research & Business Foundation Sungkyunkwan University (KR) 2012-06-07 US claimed
US-20240074682-A1 DEVICES AND METHODS FOR MEASURING A CONCENTRATION OF A TARGET ANALYTE IN A BIOLOGICAL FLUID IN VIVO DEXCOM, INC. (US) 2024-03-07 US disclosed
US-20230389844-A1 SENSING SYSTEMS AND METHODS FOR DIAGNOSING KIDNEY DISEASE DEXCOM, INC. 2023-12-07 US disclosed
US-20230390466-A1 SYSTEMS AND METHODS FOR OPTIMIZING TREATMENT USING PHYSIOLOGICAL PROFILES DEXCOM, INC. 2023-12-07 US disclosed
US-20230389833-A1 SYSTEMS AND METHODS FOR MONITORING, DIAGNOSIS, AND DECISION SUPPORT FOR DIABETES IN PATIENTS WITH KIDNEY DISEASE DEXCOM, INC. 2023-12-07 US disclosed
US-20230263434-A1 SENSING SYSTEMS AND METHODS FOR PROVIDING DECISION SUPPORT AROUND KIDNEY HEALTH AND/OR DIABETES DEXCOM, INC. 2023-08-24 US disclosed
US-8926812-B2 Cell-based transparent sensor capable of real-time optical observation of cell behavior, method for manufacturing the same and multi-detection sensor chip using the same Research & Business Foundation Sungkyunkwan University (KR) 2015-01-06 US disclosed
US-20120138458-A1 CELL-BASED TRANSPARENT SENSOR CAPABLE OF REAL-TIME OPTICAL OBSERVATION OF CELL BEHAVIOR, METHOD FOR MANUFACTURING THE SAME AND MULTI-DETECTION SENSOR CHIP USING THE SAME Research & Business Foundation Sungkyunkwan University (KR) 2012-06-07 US disclosed