SCHEMBL919951

SCHEMBL919951

CCCCCCCc1ccccn1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.67
KCNH2 Q12809 1/20 0.62
NAAA Q02083 1/20 0.56
HRH3 Q9Y5N1 2/20 0.53
LMNA P02545 3/20 0.52
ALOX15 P16050 2/20 0.52
ALDH1A1 P00352 2/20 0.52
TAAR1 Q96RJ0 1/20 0.52
CYP1A2 P05177 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
CYP2C19 P33261 2/20 0.49
CYP19A1 P11511 3/20 0.47
HRH4 Q9H3N8 1/20 0.47
KDM4E B2RXH2 2/20 0.46
USP2 O75604 1/20 0.46
ALOX12 P18054 1/20 0.46
HTT P42858 1/20 0.46
NPC1 O15118 1/20 0.46
HSP90AA1 P07900 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3672276 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL666135 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL9572197 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL25380743 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL180805 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL25381489 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL9108224 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL920310 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL21511268 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA
SCHEMBL5138374 1.00 HRH1 (0.67) HRH1KCNH2NAAAHRH3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4356894-A1 SUSTAINABLE PRODUCT WITH MALODORS Beiersdorf AG (DE) 2024-04-24 EP claimed
US-20170368019-A1 CRYSTAL FORMS OF SCUTELLARIN AGLYCONE AND PREPARATION THEREOF HLK PHARMACEUTICALS CO., LTD. (CN) 2017-12-28 US claimed
CN-104592184-A Scutellarin aglycone crystal form and preparation method thereof YUNNAN INST MATERIA MEDICA 2015-05-06 CN claimed
CN-102940224-A Cinnamamides as savory flavorings SYMRISE AG 2013-02-27 CN claimed
CN-101980619-A Taste modifying product FIRMENICH & CIE 2011-02-23 CN claimed
CN-101980620-A Product for changing taste FIRMENICH & CIE 2011-02-23 CN claimed
US-20110020517-A1 TASTE MODIFYING PRODUCT FIRMENICH SA (CH) 2011-01-27 US claimed
US-20110020518-A1 TASTE MODIFYING PRODUCT FIRMENICH SA (CH) 2011-01-27 US claimed
EP-2273894-A1 TASTE MODIFYING PRODUCT Firmenich S.A. (CH) 2011-01-19 EP claimed
EP-2262381-A2 TASTE MODIFYING PRODUCT Firmenich S.A. (CH) 2010-12-22 EP claimed
WO-2009122318-A1 TASTE MODIFYING PRODUCT FIRMENICH SA (CH) 2009-10-08 WO claimed
WO-2009122319-A2 TASTE MODIFYING PRODUCT FIRMENICH SA (CH) 2009-10-08 WO claimed
EP-1483272-B1 UREA OR CARBAMATE DERIVATIVES OF CROWN ETHERS AND SILICON USEFUL FOR THE PREPARATION OF SUPPORTS FOR CHROMATOGRAPHIC SEPARATION OF METAL CATIONS AND ORGANIC MOLECULES COMPRISING AN AMINO FUNCTION COMMISSARIAT ENERGIE ATOMIQUE (FR) 2006-01-11 EP claimed
EP-1483272-A1 UREA OR CARBAMATE DERIVATIVES OF CROWN ETHERS AND SILICON USEFUL FOR THE PREPARATION OF SUPPORTS FOR CHROMATOGRAPHIC SEPARATION OF METAL CATIONS AND ORGANIC MOLECULES COMPRISING AN AMINO FUNCTION Commissariat à l'Energie Atomique (FR) 2004-12-08 EP claimed
WO-2003062250-A1 UREA OR CARBAMATE DERIVATIVES OF CROWN ETHERS AND SILICON USEFUL FOR THE PREPARATION OF SUPPORTS FOR CHROMATOGRAPHIC SEPARATION OF METAL CATIONS AND ORGANIC MOLECULES COMPRISING AN AMINO FUNCTION COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2003-07-31 WO claimed
WO-2024098840-A1 ISOBUTYLENE-BASED CATIONIC SALT POLYMER, PREPARATION METHOD THEREFOR, USE THEREOF, AND ANTIBACTERIAL POLYMER MATERIAL 中国石油化工股份有限公司 2024-05-16 WO disclosed
CN-118027254-A Isobutylene pyridine salt ionic polymer, preparation method and application thereof, and antibacterial high polymer material 中国石油化工股份有限公司 2024-05-14 CN disclosed
US-5298486-A Orange oils for orange juice or seafood flavors FIRMENICH S.A. (CH) 1994-03-29 US disclosed
US-4118388-A OXIDATIVE DEALKYLATION CATALYST COMPOSED OF OXIDES OF VANADIUM, SILVER, AND CHROMIUM, MOLYBDENUM, OR TUNGSTEN DAICEL, LTD. (JP) 1978-10-03 US disclosed
US-4006149-A COBALT CONTAINING STUDIENGESELLSCHAFT KOHLE M.B.H. (DT) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170368019-A1 CRYSTAL FORMS OF SCUTELLARIN AGLYCONE AND PREPARATION THEREOF PCSK9, PROC, PCSK7 HRH1 3643/4885KCNH2 3122/4885NAAA 3838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.