Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 13/20 | 0.79 |
| ▸ | SRD5A1 | P18405 | 7/20 | 0.79 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9236739 | 0.91 | SRD5A2 (0.66) | SRD5A2SRD5A1ESR1ARESR2 | |
| SCHEMBL8634498 | 0.87 | SRD5A2 (0.78) | SRD5A2SRD5A1 | |
| Epristeride SCHEMBL16115063 | 0.87 | SRD5A2 (1.00) | SRD5A2SRD5A1 | |
| Epristeride SCHEMBL5444493 | 0.87 | SRD5A2 (1.00) | SRD5A2SRD5A1 | |
| Epristeride SCHEMBL61222 | 0.87 | SRD5A2 (1.00) | SRD5A2SRD5A1 | |
| Epristeride SCHEMBL23833504 | 0.87 | SRD5A2 (1.00) | SRD5A2SRD5A1 | |
| Epristeride SCHEMBL9782857 | 0.87 | SRD5A2 (0.98) | SRD5A2SRD5A1 | |
| SCHEMBL8634494 | 0.86 | SRD5A2 (0.77) | SRD5A2SRD5A1 | |
| SCHEMBL8151553 | 0.86 | SRD5A2 (0.83) | SRD5A2SRD5A1 | |
| Epristeride SCHEMBL9782855 | 0.86 | SRD5A2 (0.83) | SRD5A2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241628-A | Method for safely preparing eplerenone in one step | 江苏联环药业股份有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-119241628-A | Method for safely preparing eplerenone in one step | 江苏联环药业股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-117946200-A | Eplerenone intermediate and preparation method thereof | 江苏联环药业股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117946200-A | Eplerenone intermediate and preparation method thereof | 江苏联环药业股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| EP-0643723-A4 | HALOGENATION USING HALO-VILSMEIER REAGENT. | SMITHKLINE BEECHAM CORP (US) | 1995-05-10 | — | — | EP | disclosed |
| EP-0643723-A1 | HALOGENATION USING HALO-VILSMEIER REAGENT | SMITHKLINE BEECHAM CORPORATION (US) | 1995-03-22 | — | — | EP | disclosed |
| WO-1993014106-A1 | HALOGENATION USING HALO-VILSMEIER REAGENT | SMITHKLINE BEECHAM CORPORATION (US) | 1993-07-22 | — | — | WO | disclosed |