Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.56 |
| ▸ | MAPT | P10636 | 12/20 | 0.56 |
| ▸ | MEN1 | O00255 | 10/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10356283 | 0.77 | MAPT (0.50) | KMT2AMAPTMEN1CYP1A2ALDH1A1 | |
| SCHEMBL26948723 | 0.73 | MAPT (0.48) | KMT2AMAPTMEN1CYP1A2ALDH1A1 | |
| SCHEMBL14900321 | 0.72 | MAPT (0.49) | KMT2AMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL13479510 | 0.71 | KMT2A (0.71) | KMT2AMAPTMEN1CYP1A2ALDH1A1 | |
| SCHEMBL18481368 | 0.70 | MAPT (0.45) | KMT2AMAPTMEN1CYP1A2ALDH1A1 | |
| SCHEMBL13479537 | 0.69 | KMT2A (0.64) | KMT2AMAPTMEN1CYP1A2ALDH1A1 | |
| SCHEMBL18481370 | 0.68 | MAPT (0.47) | KMT2AMAPTMEN1CYP1A2ALDH1A1 | |
| SCHEMBL16728132 | 0.67 | MAPT (1.00) | KMT2AMAPTMEN1CYP1A2ALDH1A1 | |
| SCHEMBL26948752 | 0.67 | MAPT (0.43) | KMT2AMAPTMEN1CYP1A2ALDH1A1 | |
| SCHEMBL13186611 | 0.65 | KMT2A (0.53) | KMT2AMAPTMEN1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9249106-B2 | Substituted hydrazide compounds and use thereof | SHENYANG J & HEALTH PHARMACEUTICAL CO., LTD. (CN) | 2016-02-02 | — | — | US | disclosed |
| EP-2468730-A1 | SUBSTITUTED HYDRAZIDE COMPOUNDS AND APPLICATION THEREOF | Shenyang J & Health Pharmaceutical Co., Ltd. (CN) | 2012-06-27 | — | — | EP | disclosed |
| US-20120142921-A1 | SUBSTITUTED HYDRAZIDE COMPOUNDS AND USE THEREOF | SHENYANG J & HEALTH PHARMACEUTICAL CO., LTD. (CN) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142921-A1 | SUBSTITUTED HYDRAZIDE COMPOUNDS AND USE THEREOF | SLC5A1, VHL, AKR1A1 | KMT2A 1370/4885MAPT 3410/4885MEN1 1487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.