Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.55 |
| ▸ | HTR2A | P28223 | 3/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butylamine SCHEMBL9108736 | 0.90 | HRH1 (0.67) | HRH1HTR2AAOC3SIGMAR1LMNA | |
| SCHEMBL1973610 | 0.88 | ESR1 (0.52) | HRH1HTR2ACNR1CNR2ESR1 | |
| SCHEMBL7517085 | 0.84 | SIGMAR1 (0.50) | HRH1HTR2ACNR1CNR2ESR1 | |
| Tert-Butylamine SCHEMBL9107540 | 0.83 | CNR1 (0.45) | HRH1HTR2ACNR1CNR2ESR1 | |
| SCHEMBL27460165 | 0.83 | SIGMAR1 (0.53) | HRH1HTR2ACNR1CNR2ESR1 | |
| SCHEMBL69257 | 0.82 | ESR1 (0.57) | CNR1CNR2ESR1ESR2MEN1 | |
| Benzylamine SCHEMBL9392739 | 0.82 | ABAT (0.48) | HRH1HTR2ACNR1CNR2ESR1 | |
| SCHEMBL28822870 | 0.81 | SIGMAR1 (0.51) | HRH1HTR2ACNR1CNR2ESR1 | |
| SCHEMBL14288442 | 0.81 | SIGMAR1 (0.51) | HRH1HTR2ACNR1CNR2ESR1 | |
| SCHEMBL28035908 | 0.81 | SIGMAR1 (0.51) | HRH1HTR2ACNR1CNR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995010269-A1 | TREATMENT OF URINARY INCONTINENCE AND OTHER DISORDERS WITH R-TERODILINE AND HYDROXYLATED DERIVATIVES THEREOF | SEPRACOR, INC. (US) | 1995-04-20 | — | — | WO | claimed |
| WO-1995010270-A1 | METHOD FOR TREATING URINARY INCONTINENCE USING OPTICALLY PURE S-TERODILINE | SEPRACOR, INC. (US) | 1995-04-20 | — | — | WO | claimed |
| WO-1995010270-A1 | METHOD FOR TREATING URINARY INCONTINENCE USING OPTICALLY PURE S-TERODILINE | SEPRACOR, INC. (US) | 1995-04-20 | — | — | WO | disclosed |
| WO-1995010269-A1 | TREATMENT OF URINARY INCONTINENCE AND OTHER DISORDERS WITH R-TERODILINE AND HYDROXYLATED DERIVATIVES THEREOF | SEPRACOR, INC. (US) | 1995-04-20 | — | — | WO | disclosed |