Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29619570 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2NPSR1LOXL2IDO1HDAC6 | |
| SCHEMBL347929 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2NPSR1LOXL2IDO1HDAC6 | |
| SCHEMBL1880580 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2NPSR1LOXL2IDO1HDAC6 | |
| SCHEMBL11280915 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2NPSR1LOXL2IDO1HDAC6 | |
| 2-Mercaptobenzothiazole SCHEMBL1943715 | 0.79 | NPC1 (0.42) | SMN1; SMN2IDO1NPC1RAB9AGAA | |
| SCHEMBL9153184 | 0.72 | SMN1; SMN2 (0.82) | SMN1; SMN2NPSR1LOXL2IDO1PPARA | |
| Benzo[D]Thiazole SCHEMBL27661472 | 0.72 | ALDH1A1 (0.51) | SMN1; SMN2NPSR1LOXL2IDO1HDAC6 | |
| SCHEMBL3100845 | 0.71 | NPC1 (0.56) | SMN1; SMN2NPC1RAB9AGAAPPARA | |
| SCHEMBL9156573 | 0.70 | SMN1; SMN2 (0.60) | SMN1; SMN2NPSR1NPC1RAB9AMGAM | |
| SCHEMBL11063766 | 0.70 | NPC1 (0.54) | SMN1; SMN2NPC1RAB9AGAAPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527186-A4 | — | UNIV ILLINOIS (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0527186-A1 | PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS | The Board of Trustees for the University of Illinois (US) | 1993-02-17 | — | — | EP | disclosed |
| WO-1991016820-A1 | PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1991-11-14 | — | — | WO | disclosed |