Pyrrole

Pyrrole

SCHEMBL9109044

O=Cc1ccc[nH]1.c1cc[nH]c1

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.39
ALDH1A1 P00352 3/20 0.39
RAB9A P51151 1/20 0.39
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37
GRIN3A Q8TCU5 1/20 0.37
KDR P35968 3/20 0.36
RET P07949 2/20 0.36
PDGFRB P09619 2/20 0.36
FLT3 P36888 2/20 0.36
JAK3 P52333 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
PDPK1 O15530 2/20 0.36
SYK P43405 1/20 0.36
ATM Q13315 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19596 0.91
SCHEMBL10141206 0.91
SCHEMBL10141196 0.91
Hydrochloric Acid SCHEMBL28194910 0.88
Bromide SCHEMBL17747828 0.88
SCHEMBL27449483 0.88
Benzene SCHEMBL28236469 0.86 MAPT (0.46) MAPTALDH1A1RAB9AGRIN2DGRIN3B
Ethyne SCHEMBL7797558 0.86
SCHEMBL27437455 0.86 MAPT (0.46) MAPTALDH1A1RAB9AGRIN2DGRIN3B
Methyl Alcohol SCHEMBL11864407 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0527186-A4 UNIV ILLINOIS (US) 1995-01-18 EP disclosed
EP-0527186-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS The Board of Trustees for the University of Illinois (US) 1993-02-17 EP disclosed
WO-1991016820-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1991-11-14 WO disclosed