⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19596 | 1.00 | — | — | |
| SCHEMBL10141196 | 1.00 | — | — | |
| Bromide SCHEMBL17747828 | 0.97 | — | — | |
| Ethyne SCHEMBL7797558 | 0.95 | — | — | |
| Methyl Alcohol SCHEMBL11864407 | 0.93 | — | — | |
| Pyrrole SCHEMBL9109044 | 0.91 | MAPT (0.39) | — | |
| Cyanamide SCHEMBL28845026 | 0.87 | ALDH1A1 (0.42) | — | |
| Aniline SCHEMBL29082335 | 0.85 | TSHR (0.44) | — | |
| SCHEMBL28725984 | 0.83 | ALDH1A1 (0.39) | — | |
| SCHEMBL3862048 | 0.83 | KMT2A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 700 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480465-B | Preparation method of 1- (2-nitrobenzyl) pyrrole-2-formaldehyde | 埃斯特维华义制药有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-114502537-A | Mutant IDH2 inhibitor and application thereof | 贝达药业股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-113480465-A | Preparation method of 1- (2-nitrobenzyl) pyrrole-2-formaldehyde | 埃斯特维华义制药有限公司 | 2021-10-08 | — | — | CN | claimed |
| CN-111575106-A | Sesame oil squeezing method and equipment and prepared sesame oil | 青岛嘉里花生油有限公司 | 2020-08-25 | — | — | CN | claimed |
| CN-105779108-B | Sesame oil squeezing method and equipment and prepared sesame oil | 青岛嘉里花生油有限公司 | 2020-06-30 | — | — | CN | claimed |
| US-20260109699-A1 | AZOLE DERIVATIVES AS SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2026-04-23 | — | — | US | disclosed |
| US-20260078131-A1 | PYRROLO-PYRIDAZINE INHIBITORS OF JAK2 | AJAX THERAPEUTICS INC (US) | 2026-03-19 | — | — | US | disclosed |
| US-12570651-B2 | Quinazoline-2,4-dione derivatives as PARP inhibitors | Suzhou Four Health Pharmaceuticals Co., Ltd. (CN) | 2026-03-10 | — | — | US | disclosed |
| US-20260062416-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS INC (US) | 2026-03-05 | — | — | US | disclosed |
| EP-4655069-A1 | PYRIDAZINES AS SARM1 INHIBITORS | Disarm Therapeutics, Inc. (US) | 2025-12-03 | — | — | EP | disclosed |
| EP-4619101-A1 | NOVEL PYRROLO[1,2-d][1,2,4]TRIAZINONE DERIVATIVES AS NEGATIVE ALLOSTERIC MODULATORS OF MGLU7 RECEPTORS | Neurosterix Pharma Sàrl (CH) | 2025-09-24 | — | — | EP | disclosed |
| EP-4608831-A1 | COMPOUNDS AND USES THEREOF | Suzhou Zanrong Pharma Limited (CN) | 2025-09-03 | — | — | EP | disclosed |
| US-20030229108-A1 | Barbituric acid analogs as therapeutic agents | NOVUSPHARMA S.P.A. (IT) | 2003-12-11 | — | — | US | disclosed |
| US-20030162785-A1 | Protein kinase inhibitors | ABBVIE INC. | 2003-08-28 | — | — | US | disclosed |
| US-20030119839-A1 | Protein kinase inhibitors | ABBOTT LABORATORIES | 2003-06-26 | — | — | US | disclosed |
| US-6534524-B1 | Antiproliferative agents, including axitinib | AGOURON PHARMACEUTICALS, INC. | 2003-03-18 | — | — | US | disclosed |
| US-6531491-B1 | Methods of treating cancer and other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis, | AGOURON PHARAMACEUTICALS, INC. | 2003-03-11 | — | — | US | disclosed |
| US-20030045728-A1 | Liberating 3-substituted indole compound from one of its functional derivatives by treatment with a solvolyzing or hydrogenating agent, amidation, saponification, alkylation or acylation, or salt formation | MERCK PATENT GMBH (DE) | 2003-03-06 | — | — | US | disclosed |
| US-20020091148-A1 | 3-substituted indole antiproliferative angiogenesis inhibitors | ABBOTT LABORATORIES | 2002-07-11 | — | — | US | disclosed |
| US-6323228-B1 | INHIBITING ANGIOGENESIS IN A MAMMAL IN RECOGNIZED NEED OF SUCH TREATMENT COMPRISING ADMINISTERING TO THE MAMMAL WITH INDOLE SUBSTITUTED WITH HYDRAZIDES | ABBOTT LABORATORIES | 2001-11-27 | — | — | US | disclosed |