Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 2/20 | 0.31 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.30 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8283346 | 0.91 | — | — | |
| SCHEMBL879375 | 0.78 | CYP19A1 (0.39) | CYP19A1ALDH1A1EGLN3WEE1MAPT | |
| SCHEMBL7033719 | 0.75 | CYP19A1 (0.37) | CYP19A1ALDH1A1EGLN3CYP24A1MAPT | |
| SCHEMBL6425055 | 0.75 | — | — | |
| SCHEMBL6735760 | 0.74 | ALDH1A1 (0.43) | CYP19A1ALDH1A1EGLN3MAPTTBXAS1 | |
| SCHEMBL11463256 | 0.74 | EGLN3 (0.45) | ALDH1A1EGLN3WEE1MAPTTBXAS1 | |
| SCHEMBL8761373 | 0.72 | — | — | |
| SCHEMBL28410390 | 0.72 | ALDH1A1 (0.38) | CYP19A1ALDH1A1EGLN3WEE1MAPT | |
| SCHEMBL1161357 | 0.71 | — | — | |
| SCHEMBL22117141 | 0.71 | EGLN3 (0.42) | ALDH1A1EGLN3WEE1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605627-A4 | IMMUNOASSAY FOR IDENTIFYING ALCOHOLICS AND MONITORING ALCOHOL CONSUMPTION. | MAKHLOUF SAMAR (US) | 1995-03-29 | — | — | EP | disclosed |
| EP-0605627-A1 | IMMUNOASSAY FOR IDENTIFYING ALCOHOLICS AND MONITORING ALCOHOL CONSUMPTION | MAKHLOUF, Samar (US) | 1994-07-13 | — | — | EP | disclosed |
| WO-1993006133-A1 | IMMUNOASSAY FOR IDENTIFYING ALCOHOLICS AND MONITORING ALCOHOL CONSUMPTION | MAKHLOUF SAMAR (US) | 1993-04-01 | — | — | WO | disclosed |