Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.54 |
| ▸ | CTSK | P43235 | 6/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9109424 | 0.92 | CTSC (0.52) | CTSCCTSKKCNH2LTB4RLTB4R2 | |
| SCHEMBL9888342 | 0.89 | CTSC (0.50) | CTSCCTSKKCNH2LTB4RLTB4R2 | |
| SCHEMBL7876862 | 0.89 | CTSC (0.50) | CTSCCTSKKCNH2LTB4RLTB4R2 | |
| SCHEMBL2891014 | 0.88 | CTSC (0.70) | CTSCCTSKKCNH2LTB4RLTB4R2 | |
| SCHEMBL2888991 | 0.88 | CTSC (0.70) | CTSCCTSKKCNH2LTB4RLTB4R2 | |
| SCHEMBL2887671 | 0.85 | CTSC (0.51) | CTSCCTSKKCNH2LTB4RLTB4R2 | |
| Trifluoroacetic Acid SCHEMBL2888927 | 0.85 | CTSC (0.64) | CTSCCTSKKCNH2LTB4RLTB4R2 | |
| SCHEMBL2890645 | 0.85 | CTSC (0.68) | CTSCCTSKKCNH2LTB4RLTB4R2 | |
| SCHEMBL2890779 | 0.83 | CTSC (0.54) | CTSCCTSKKCNH2LTB4RLTB4R2 | |
| SCHEMBL2890780 | 0.81 | CTSC (0.54) | CTSCCTSKKCNH2LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193239-B2 | Substituted 1-cyanoethylheterocyclylcarboxamide compounds | ASTRAZENECA AB (SE) | 2012-06-05 | — | — | US | disclosed |