Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9109428 | 1.00 | HRH3 (0.42) | HRH3LMNAALDH1A1MAPTPOLB | |
| SCHEMBL9110726 | 0.98 | HRH3 (0.39) | HRH3LMNAALDH1A1MAPTPOLB | |
| SCHEMBL9110730 | 0.98 | HRH3 (0.39) | HRH3LMNAALDH1A1MAPTPOLB | |
| SCHEMBL9111421 | 0.79 | HRH3 (0.44) | HRH3LMNAALDH1A1MAPTPOLB | |
| SCHEMBL9111427 | 0.79 | HRH3 (0.44) | HRH3LMNAALDH1A1MAPTPOLB | |
| SCHEMBL9111828 | 0.78 | POLB (0.41) | ALDH1A1MAPTPOLBSMN1; SMN2SIGMAR1 | |
| SCHEMBL9111836 | 0.78 | POLB (0.41) | ALDH1A1MAPTPOLBSMN1; SMN2SIGMAR1 | |
| SCHEMBL9111941 | 0.76 | HRH3 (0.40) | HRH3LMNAALDH1A1MAPTPOLB | |
| SCHEMBL9111952 | 0.76 | HRH3 (0.40) | HRH3LMNAALDH1A1MAPTPOLB | |
| SCHEMBL818010 | 0.76 | HRH3 (0.41) | HRH3LMNAALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |