Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9111828 | 1.00 | POLB (0.41) | POLBSMN1; SMN2CXCR4RAD52HSD17B10 | |
| SCHEMBL9113900 | 0.81 | POLB (0.42) | POLBSMN1; SMN2CXCR4RAD52HSD17B10 | |
| SCHEMBL9113910 | 0.81 | POLB (0.42) | POLBSMN1; SMN2CXCR4RAD52HSD17B10 | |
| SCHEMBL9110726 | 0.80 | HRH3 (0.39) | POLBSMN1; SMN2SIGMAR1ALDH1A1MAPT | |
| SCHEMBL9110730 | 0.80 | HRH3 (0.39) | POLBSMN1; SMN2SIGMAR1ALDH1A1MAPT | |
| SCHEMBL9109433 | 0.78 | HRH3 (0.42) | POLBSMN1; SMN2HSD17B10SIGMAR1ALDH1A1 | |
| SCHEMBL9109428 | 0.78 | HRH3 (0.42) | POLBSMN1; SMN2HSD17B10SIGMAR1ALDH1A1 | |
| SCHEMBL28832350 | 0.77 | SMN1; SMN2 (0.42) | POLBSMN1; SMN2CXCR4RAD52HSD17B10 | |
| SCHEMBL136968 | 0.76 | POLB (0.45) | POLBSMN1; SMN2CXCR4RAD52HSD17B10 | |
| SCHEMBL4508116 | 0.75 | POLB (0.48) | POLBSMN1; SMN2CXCR4RAD52HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |