Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | RBBP9 | O75884 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CASP3 | P42574 | 3/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochlorthiazide SCHEMBL15798726 | 1.00 | ALDH1A1 (0.72) | ALDH1A1RBBP9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL247631 | 0.85 | — | — | |
| Bromide SCHEMBL27358834 | 0.83 | — | — | |
| Pyridine SCHEMBL28239898 | 0.79 | ALDH1A1 (0.78) | ALDH1A1RBBP9CYP1A2CYP2D6CYP2C19 | |
| Hydrochlorthiazide SCHEMBL17201627 | 0.79 | ALDH1A1 (0.44) | ALDH1A1RBBP9CYP1A2CYP2D6CYP2C19 | |
| Hydrochlorthiazide SCHEMBL28321063 | 0.77 | — | — | |
| Hydrochlorthiazide SCHEMBL15656554 | 0.77 | — | — | |
| Piperazine SCHEMBL27346745 | 0.75 | ALDH1A1 (0.78) | ALDH1A1RBBP9CYP1A2CYP2D6CYP2C19 | |
| Hydrochlorthiazide SCHEMBL4940467 | 0.75 | ALDH1A1 (0.32) | ALDH1A1 | |
| Hydrochlorthiazide SCHEMBL10585431 | 0.75 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527186-A4 | — | UNIV ILLINOIS (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0527186-A1 | PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS | The Board of Trustees for the University of Illinois (US) | 1993-02-17 | — | — | EP | disclosed |
| WO-1991016820-A1 | PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1991-11-14 | — | — | WO | disclosed |