Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 16/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.52 |
| ▸ | ESRRG | P62508 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9107032 | 0.85 | HDAC3 (0.65) | HDAC3HDAC1HDAC2ESRRGNCOR2 | |
| SCHEMBL2654333 | 0.82 | HDAC3 (0.58) | HDAC3HDAC1HDAC2ESRRGNCOR2 | |
| SCHEMBL9109090 | 0.81 | HDAC3 (0.74) | HDAC3HDAC1HDAC2NCOR2HDAC6 | |
| SCHEMBL9110617 | 0.80 | HDAC3 (0.59) | HDAC3HDAC1HDAC2NCOR2NPC1 | |
| SCHEMBL2995407 | 0.78 | RAB9A (0.72) | HDAC3HDAC1HDAC2HDAC6NPC1 | |
| SCHEMBL2652265 | 0.77 | SMN1; SMN2 (0.59) | HDAC3HDAC1HDAC2NCOR2HDAC6 | |
| SCHEMBL9110278 | 0.76 | RAB9A (0.67) | HDAC3HDAC1HDAC2HDAC6NPC1 | |
| SCHEMBL3237303 | 0.76 | HDAC1 (0.65) | HDAC3HDAC1HDAC2HDAC6NPC1 | |
| SCHEMBL9109405 | 0.75 | HDAC3 (0.80) | HDAC3HDAC1HDAC2NCOR2NPC1 | |
| SCHEMBL17141809 | 0.75 | HDAC3 (0.83) | HDAC3HDAC1HDAC2NCOR2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0631571-A1 | PREPARATION OF OPTICALLY ACTIVE HYDRAZINES AND AMINES. | DU PONT (US) | 1995-01-04 | — | — | EP | disclosed |