Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 3/20 | 0.59 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM4B | O94953 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9110151 | 1.00 | CREBBP (0.59) | CREBBPBRPF1GSK3BTSHRKDM4A | |
| SCHEMBL9414037 | 0.93 | CREBBP (0.59) | CREBBPBRPF1GSK3BTSHRKDM4A | |
| Hydrochloric Acid SCHEMBL15953312 | 0.91 | CREBBP (0.58) | CREBBPBRPF1GSK3BTSHRKDM4A | |
| SCHEMBL1101924 | 0.75 | CREBBP (1.00) | CREBBPBRPF1GSK3BTSHRMEN1 | |
| SCHEMBL10327064 | 0.75 | CREBBP (1.00) | CREBBPBRPF1GSK3BTSHRMEN1 | |
| SCHEMBL7668762 | 0.75 | CREBBP (1.00) | CREBBPBRPF1GSK3BTSHRMEN1 | |
| SCHEMBL13185757 | 0.73 | PDE3B (0.43) | CREBBPBRPF1GSK3BKDM4AKDM4B | |
| SCHEMBL15314282 | 0.73 | PDE3B (0.43) | CREBBPBRPF1GSK3BKDM4AKDM4B | |
| SCHEMBL25059407 | 0.72 | ADORA3 (0.35) | MEN1KMT2AADORA3ADORA2AADORA1 | |
| SCHEMBL9110204 | 0.70 | GSK3B (0.45) | CREBBPBRPF1GSK3BTSHRXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424311-A | A viricides for treating viral diseases; HIV enzyme inhibitor | HOESCHST AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |
| EP-0590428-A1 | Azaquinoxalines, process for their preparation, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |