Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9110204 | 1.00 | GSK3B (0.45) | GSK3BBRPF1CREBBPTSHRXIAP | |
| SCHEMBL9107035 | 0.86 | GSK3B (0.57) | GSK3BBRPF1CREBBPTSHRXIAP | |
| SCHEMBL9107039 | 0.86 | GSK3B (0.57) | GSK3BBRPF1CREBBPTSHRXIAP | |
| SCHEMBL26634379 | 0.74 | KDM4E (0.35) | — | |
| SCHEMBL26634374 | 0.74 | KDM4E (0.35) | — | |
| SCHEMBL26634369 | 0.74 | KDM4E (0.35) | — | |
| SCHEMBL31689200 | 0.74 | KDM4E (0.35) | — | |
| SCHEMBL3955042 | 0.74 | HSP90AA1 (0.40) | HSP90AA1 | |
| SCHEMBL29977891 | 0.74 | HSP90AA1 (0.40) | HSP90AA1 | |
| SCHEMBL14952335 | 0.73 | GSK3B (0.43) | GSK3BBRPF1CREBBPTSHRXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218865-A | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2021-01-12 | — | — | CN | disclosed |
| US-5424311-A | A viricides for treating viral diseases; HIV enzyme inhibitor | HOESCHST AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |
| EP-0590428-A1 | Azaquinoxalines, process for their preparation, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |