Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9107035 | 1.00 | GSK3B (0.57) | GSK3BBRPF1CREBBPTSHRHSP90AA1 | |
| SCHEMBL9110195 | 0.86 | GSK3B (0.45) | GSK3BBRPF1CREBBPTSHRHSP90AA1 | |
| SCHEMBL9110204 | 0.86 | GSK3B (0.45) | GSK3BBRPF1CREBBPTSHRHSP90AA1 | |
| SCHEMBL29977891 | 0.74 | HSP90AA1 (0.40) | HSP90AA1NNMT | |
| SCHEMBL3955042 | 0.74 | HSP90AA1 (0.40) | HSP90AA1NNMT | |
| SCHEMBL7693095 | 0.72 | HSP90AA1 (0.39) | HSP90AA1NNMT | |
| SCHEMBL19153676 | 0.71 | PDE3B (0.40) | GSK3BNNMTMKNK2 | |
| SCHEMBL9110149 | 0.70 | CREBBP (0.59) | GSK3BBRPF1CREBBPTSHRXIAP | |
| SCHEMBL9414037 | 0.70 | CREBBP (0.59) | GSK3BBRPF1CREBBPTSHRXIAP | |
| SCHEMBL9110151 | 0.70 | CREBBP (0.59) | GSK3BBRPF1CREBBPTSHRXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424311-A | A viricides for treating viral diseases; HIV enzyme inhibitor | HOESCHST AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |