Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22190326 | 0.82 | NPC1 (0.54) | NPC1RAB9AALDH1A1HSD17B10MAPT | |
| SCHEMBL57538 | 0.82 | NPC1 (0.54) | NPC1RAB9AALDH1A1HSD17B10MAPT | |
| Oxazole SCHEMBL9110217 | 0.81 | NPC1 (0.40) | NPC1RAB9AALDH1A1HSD17B10MAPT | |
| Fluoride SCHEMBL31379725 | 0.80 | NPC1 (0.52) | NPC1RAB9AALDH1A1HSD17B10MAPT | |
| SCHEMBL4915686 | 0.80 | NPC1 (0.52) | NPC1RAB9AALDH1A1HSD17B10MAPT | |
| SCHEMBL16238046 | 0.80 | NPC1 (0.52) | NPC1RAB9AALDH1A1HSD17B10MAPT | |
| SCHEMBL9151264 | 0.80 | NPC1 (0.52) | NPC1RAB9AALDH1A1HSD17B10MAPT | |
| SCHEMBL11211888 | 0.80 | NPC1 (0.52) | NPC1RAB9AALDH1A1HSD17B10MAPT | |
| SCHEMBL7435020 | 0.80 | NPC1 (0.52) | NPC1RAB9AALDH1A1HSD17B10MAPT | |
| Oxazole SCHEMBL28451950 | 0.79 | ALDH1A1 (0.49) | NPC1RAB9AALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527186-A4 | — | UNIV ILLINOIS (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0527186-A1 | PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS | The Board of Trustees for the University of Illinois (US) | 1993-02-17 | — | — | EP | disclosed |
| WO-1991016820-A1 | PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1991-11-14 | — | — | WO | disclosed |