Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9109996 | 1.00 | HDAC4 (0.42) | HDAC4MEF2DCYP4F2CYP4A11TP53 | |
| SCHEMBL16167528 | 0.85 | HDAC4 (0.43) | HDAC4MEF2DCYP4F2CYP4A11TP53 | |
| SCHEMBL16167524 | 0.85 | HDAC4 (0.43) | HDAC4MEF2DCYP4F2CYP4A11TP53 | |
| SCHEMBL10858214 | 0.81 | ALDH1A1 (0.47) | HDAC4MEF2DCYP4F2CYP4A11TP53 | |
| SCHEMBL29239895 | 0.81 | HDAC4 (0.42) | HDAC4MEF2DCYP4F2CYP4A11TP53 | |
| SCHEMBL10987751 | 0.81 | HDAC4 (0.43) | HDAC4MEF2DCYP4F2CYP4A11TP53 | |
| SCHEMBL29674000 | 0.80 | HDAC4 (0.49) | HDAC4MEF2DTP53DHODHPTGS2 | |
| SCHEMBL318201 | 0.80 | HDAC4 (0.49) | HDAC4MEF2DTP53DHODHPTGS2 | |
| SCHEMBL318202 | 0.80 | HDAC4 (0.49) | HDAC4MEF2DTP53DHODHPTGS2 | |
| SCHEMBL30641423 | 0.79 | HDAC4 (0.40) | HDAC4MEF2DCYP4F2CYP4A11TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |