SCHEMBL9110548

SCHEMBL9110548

Cc1cc(-c2ccccc2)cc(C)c1C1C(=O)C2C3CCC(O3)C2C1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.43
BRD4 O60885 1/20 0.36
LMNA P02545 2/20 0.34
ALDH1A1 P00352 1/20 0.34
CNR1 P21554 2/20 0.33
CNR2 P34972 2/20 0.33
TFPI2 P48307 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
PPM1B O75688 1/20 0.33
PPP1CC P36873 1/20 0.33
RAB9A P51151 1/20 0.33
PPP5C P53041 1/20 0.33
PPP1CA P62136 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 1/20 0.33
CYP2D6 P10635 1/20 0.33
NFKB1 P19838 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6727349 1.00 L3MBTL1 (0.43) L3MBTL1BRD4LMNAALDH1A1CNR1
SCHEMBL18874380 1.00 L3MBTL1 (0.43) L3MBTL1BRD4LMNAALDH1A1CNR1
SCHEMBL6727399 0.89 L3MBTL1 (0.38) L3MBTL1LMNAALDH1A1TFPI2KDM4E
SCHEMBL18873798 0.89 L3MBTL1 (0.38) L3MBTL1LMNAALDH1A1TFPI2KDM4E
SCHEMBL6727333 0.86 L3MBTL1 (0.36) L3MBTL1LMNAALDH1A1TFPI2KDM4E
SCHEMBL18874115 0.86 L3MBTL1 (0.36) L3MBTL1LMNACNR1CNR2PDE3B
SCHEMBL18874255 0.86 L3MBTL1 (0.36) L3MBTL1LMNAALDH1A1TFPI2KDM4E
SCHEMBL6727919 0.86 L3MBTL1 (0.36) L3MBTL1LMNACNR1CNR2PDE3B
SCHEMBL18873881 0.85 ESR2 (0.40) L3MBTL1BACE1
SCHEMBL6727370 0.85 ESR2 (0.40) L3MBTL1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2173755-B1 NOVEL HERBICIDES SYNGENTA LTD (GB) 2017-05-17 EP disclosed
US-8940913-B2 Herbicides SYNGENTA CROP PROTECTION, LLC (US) 2015-01-27 US disclosed
US-20120142529-A1 NOVEL HERBICIDES SYNGENTA CROP PROTECTION, INC. (US) 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142529-A1 NOVEL HERBICIDES DDT, CYP4X1, CYP1B1 L3MBTL1 1453/4885BRD4 2341/4885LMNA 4657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.