Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854817 | 1.00 | TSHR (0.54) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL4854824 | 1.00 | TSHR (0.54) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL19282565 | 0.90 | — | — | |
| SCHEMBL3078400 | 0.82 | TSHR (0.62) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL2869472 | 0.82 | TSHR (0.62) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL1395419 | 0.82 | TSHR (0.62) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL1114864 | 0.82 | TSHR (0.62) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL1076957 | 0.82 | TSHR (0.62) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL10980289 | 0.82 | TSHR (0.62) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL169329 | 0.82 | TSHR (0.62) | TSHRALDH1A1THRBFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |