SCHEMBL169329

SCHEMBL169329

C=C[CH]CCCCCCCCCCCCCCCCCC

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.62
ALDH1A1 P00352 1/20 0.46
THRB P10828 1/20 0.44
FAAH O00519 3/20 0.42
TRPV1 Q8NER1 1/20 0.42
DNM1 Q05193 3/20 0.41
EP300 Q09472 1/20 0.38
MEN1 O00255 1/20 0.38
CYP3A4 P08684 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1705800 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL2871946 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL3078400 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL1114864 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL1076957 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL2869472 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL1395419 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL10980289 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL298912 1.00
SCHEMBL2859340 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024123720-A1 COATED ARTICLES WITH AN ANTI-FINGERPRINT COATING OR SURFACE-MODIFYING LAYER AND METHODS OF MAKING THE SAME CORNING INCORPORATED (US) 2024-06-13 WO claimed
US-20230182110-A1 METHOD AND MATERIALS FOR EXTRACTION OF OIL-SOLUBLE ORGANIC MOLECULAR TRACERS FROM OIL PHASES SAUDI ARABIAN OIL COMPANY (SA) 2023-06-15 US claimed
US-20200352900-A1 IMPROVED PEPTIDE PHARMACEUTICALS FOR TREATMENT OF NASH AND OTHER DISORDERS MEDERIS DIABETES LLC (US) 2020-11-12 US claimed
EP-3735295-A1 IMPROVED PEPTIDE PHARMACEUTICALS FOR TREATMENT OF NASH AND OTHER DISORDERS Mederis Diabetes, LLC (US) 2020-11-11 EP claimed
WO-2019136158-A1 IMPROVED PEPTIDE PHARMACEUTICALS FOR TREATMENT OF NASH AND OTHER DISORDERS SPITFIRE PHARMA, INC. (US) 2019-07-11 WO claimed
CN-106661097-A Improved peptide drugs against insulin resistance 梅德瑞斯糖尿病有限责任公司 2017-05-10 CN claimed
EP-3155017-A1 IMPROVED PEPTIDE PHARMACEUTICALS FOR INSULIN RESISTANCE Mederis Diabetes, LLC (US) 2017-04-19 EP claimed
US-20170096468-A1 IMPROVED PEPTIDE PHARMACEUTICALS FOR INSULIN RESISTANCE HERCULES CAPITAL, INC., AS AGENT 2017-04-06 US claimed
EP-2376221-B1 MODIFIED CLAY SORBENTS CRC CARE PTY LTD (AU) 2017-03-15 EP claimed
CN-105646777-A Hydrophobic associated polymer and preparation method thereof 四川光亚聚合物化工有限公司 2016-06-08 CN claimed
EP-2376221-A1 MODIFIED CLAY SORBENTS CRC Care Pty Ltd (AU) 2011-10-19 EP claimed
CN-102138869-A Peptide-based conditioner and colorant for hair, skin and nail DU PONT 2011-08-03 CN claimed
CN-1863501-B Peptide-based conditioners and colorants for hair, skin and nails DU PONT 2011-05-25 CN claimed
WO-2010065996-A1 MODIFIED CLAY SORBENTS CRC CARE PTY LTD (AU) 2010-06-17 WO claimed
CN-101453981-A Peptide-based body surface coloring reagents DU PONT (US) 2009-06-10 CN claimed
CN-1296397-C Antibacterial high water-absorbent resin and method for preparation thereof ZHONGKAI AGROTECHNICAL COLLEGE (CN) 2007-01-24 CN claimed
CN-1863501-A Peptide-based conditioners and colorants for hair, skin and nails DU PONT (US) 2006-11-15 CN claimed
CN-1670047-A Antibacterial high water-absorbent resin and method for preparation thereof ZHONGKAI AGROTECHNICAL COLLEGE (CN) 2005-09-21 CN claimed
US-4726945-A MIXTURE OF QUATERNARY AMMONIUM COMPOUND, ALKYLAMIDODIALKYLAMINE, PROPYLENE GLYCOL, MINERAL OIL, FATTY ALCOHOL AND SILOXANE COLGATE-PALMOLIVE CO. (US) 1988-02-23 US claimed
US-3951857-A TRIS(ALKYL)PHOSPHORIC TRIAMIDE TEXACO INC. (US) 1976-04-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170096468-A1 IMPROVED PEPTIDE PHARMACEUTICALS FOR INSULIN RESISTANCE IAPP, PTMS, GLP1R TSHR 268/4885ALDH1A1 4702/4885THRB 317/4885
US-20200352900-A1 IMPROVED PEPTIDE PHARMACEUTICALS FOR TREATMENT OF NASH AND OTHER DISORDERS IAPP, GLP1R, FABP4 TSHR 767/4885ALDH1A1 4659/4885THRB 1200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.