Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18595954 | 1.00 | BRD4 (0.39) | BRD4MMP2ANPEPCYP1A2CYP3A4 | |
| SCHEMBL9110589 | 1.00 | BRD4 (0.39) | BRD4MMP2ANPEPCYP1A2CYP3A4 | |
| SCHEMBL3056179 | 1.00 | BRD4 (0.39) | BRD4MMP2ANPEPCYP1A2CYP3A4 | |
| SCHEMBL12294236 | 1.00 | BRD4 (0.39) | BRD4MMP2ANPEPCYP1A2CYP3A4 | |
| SCHEMBL2372196 | 0.91 | BRD4 (0.44) | BRD4MMP2ANPEPCYP1A2CYP3A4 | |
| SCHEMBL994649 | 0.91 | BRD4 (0.44) | BRD4MMP2ANPEPCYP1A2CYP3A4 | |
| SCHEMBL3048242 | 0.91 | BRD4 (0.44) | BRD4MMP2ANPEPCYP1A2CYP3A4 | |
| SCHEMBL7858138 | 0.91 | BRD4 (0.44) | BRD4MMP2ANPEPCYP1A2CYP3A4 | |
| SCHEMBL15684230 | 0.91 | BRD4 (0.44) | BRD4MMP2ANPEPCYP1A2CYP3A4 | |
| SCHEMBL2172703 | 0.85 | THRB (0.39) | BRD4MMP2ANPEPCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315834-A | Imidazolidinone derivatives and their use in medicaments | 成都百裕制药股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| WO-1995007022-A1 | FUNGICIDES | ZENECA LIMITED (GB) | 1995-03-16 | — | — | WO | disclosed |