Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9114632 | 0.94 | MAGI3 (0.52) | MAGI3EDNRAKMT2AL3MBTL1MMP1 | |
| SCHEMBL9110705 | 0.87 | MAGI3 (0.65) | MAGI3EDNRAKMT2AL3MBTL1ACE | |
| SCHEMBL9143412 | 0.87 | MAGI3 (0.65) | MAGI3EDNRAKMT2AL3MBTL1ACE | |
| SCHEMBL9143425 | 0.87 | MAGI3 (0.65) | MAGI3EDNRAKMT2AL3MBTL1ACE | |
| SCHEMBL9110690 | 0.87 | MAGI3 (0.65) | MAGI3EDNRAKMT2AL3MBTL1ACE | |
| SCHEMBL9114918 | 0.81 | MAGI3 (0.69) | MAGI3EDNRAKMT2AL3MBTL1MMP1 | |
| SCHEMBL9141715 | 0.81 | MAGI3 (0.69) | MAGI3EDNRAKMT2AL3MBTL1MMP1 | |
| SCHEMBL9114908 | 0.81 | MAGI3 (0.69) | MAGI3EDNRAKMT2AL3MBTL1MMP1 | |
| SCHEMBL9141706 | 0.81 | MAGI3 (0.69) | MAGI3EDNRAKMT2AL3MBTL1MMP1 | |
| SCHEMBL30051825 | 0.81 | ACE (0.64) | EDNRAKMT2AL3MBTL1ACEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652897-A4 | PEPTIDE INHIBITORS OF SELECTIN BINDING. | CENTOCOR INC (US) | 1995-09-20 | — | — | EP | disclosed |
| EP-0652897-A1 | PEPTIDE INHIBITORS OF SELECTIN BINDING | CENTOCOR INC. (US) | 1995-05-17 | — | — | EP | disclosed |
| WO-1993024527-A1 | PEPTIDE INHIBITORS OF SELECTIN BINDING | CENTOCOR, INC. (US) | 1993-12-09 | — | — | WO | disclosed |