SCHEMBL9110694

SCHEMBL9110694

C=CCOc1ccc(C(=O)C=Cc2cc(OCCCC)cc(OCCCC)c2C(C)(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 7/20 0.50
ABCG2 Q9UNQ0 2/20 0.50
DPP4 P27487 3/20 0.49
CYP1A1 P04798 2/20 0.46
CYP1B1 Q16678 2/20 0.46
BCHE P06276 4/20 0.45
ACHE P22303 2/20 0.45
PPARA Q07869 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9114988 0.96 CYP1A1 (0.51) PTPN1ABCG2DPP4CYP1A1CYP1B1
SCHEMBL9114693 0.91 CYP1A1 (0.55) PTPN1ABCG2DPP4CYP1A1CYP1B1
SCHEMBL9110872 0.90 PTPN1 (0.52) PTPN1ABCG2DPP4CYP1A1CYP1B1
SCHEMBL9113947 0.90 ABCG2 (0.54) PTPN1ABCG2DPP4CYP1A1CYP1B1
SCHEMBL9112357 0.89 CYP1A1 (0.57) PTPN1ABCG2DPP4CYP1A1CYP1B1
SCHEMBL9112441 0.88 ABCG2 (0.63) PTPN1ABCG2DPP4CYP1A1CYP1B1
SCHEMBL9113931 0.88 DPP4 (0.55) PTPN1ABCG2DPP4CYP1A1CYP1B1
SCHEMBL9115147 0.87 ABCG2 (0.56) PTPN1ABCG2CYP1A1CYP1B1BCHE
SCHEMBL9112250 0.87 PTPN1 (0.55) PTPN1ABCG2DPP4CYP1A1CYP1B1
SCHEMBL9113361 0.86 CYP1A1 (0.54) ABCG2DPP4CYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995006628-A1 TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA STATENS SERUMINSTITUT (DK) 1995-03-09 WO claimed
WO-1995006628-A1 TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA STATENS SERUMINSTITUT (DK) 1995-03-09 WO disclosed