SCHEMBL9114693

SCHEMBL9114693

CCCCOc1cc(C=CC(=O)c2ccc(OCCC)cc2)c(C(C)(C)C)c(OCCCC)c1

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 2/20 0.55
CYP1B1 Q16678 2/20 0.55
ABCG2 Q9UNQ0 2/20 0.55
DPP4 P27487 3/20 0.53
PTPN1 P18031 1/20 0.53
BCHE P06276 10/20 0.49
ACHE P22303 8/20 0.48
PPARA Q07869 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9112357 0.98 CYP1A1 (0.57) CYP1A1CYP1B1ABCG2DPP4PTPN1
SCHEMBL9113361 0.95 CYP1A1 (0.54) CYP1A1CYP1B1ABCG2DPP4
SCHEMBL9113947 0.95 ABCG2 (0.54) CYP1A1CYP1B1ABCG2DPP4PTPN1
SCHEMBL9112441 0.93 ABCG2 (0.63) CYP1A1CYP1B1ABCG2DPP4PTPN1
SCHEMBL9113931 0.93 DPP4 (0.55) CYP1A1CYP1B1ABCG2DPP4PTPN1
SCHEMBL9112902 0.93 CYP1A1 (0.59) CYP1A1CYP1B1ABCG2DPP4PTPN1
SCHEMBL9115056 0.93 CYP1A1 (0.54) CYP1A1CYP1B1ABCG2DPP4
SCHEMBL9113109 0.91 ABCG2 (0.61) CYP1A1CYP1B1ABCG2DPP4PTPN1
SCHEMBL9114988 0.91 CYP1A1 (0.51) CYP1A1CYP1B1ABCG2DPP4PTPN1
SCHEMBL9110694 0.91 PTPN1 (0.50) CYP1A1CYP1B1ABCG2DPP4PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995006628-A1 TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA STATENS SERUMINSTITUT (DK) 1995-03-09 WO claimed