Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18112860 | 1.00 | TSHR (0.44) | TSHRGAALMNAMEN1KMT2A | |
| SCHEMBL29360940 | 1.00 | TSHR (0.44) | TSHRGAALMNAMEN1KMT2A | |
| SCHEMBL19176101 | 0.92 | TSHR (0.41) | TSHRGAALMNAMEN1KMT2A | |
| SCHEMBL29458581 | 0.92 | TSHR (0.41) | TSHRGAALMNAMEN1KMT2A | |
| SCHEMBL18131639 | 0.92 | TSHR (0.41) | TSHRGAALMNAMEN1KMT2A | |
| SCHEMBL19176033 | 0.91 | TSHR (0.41) | TSHRGAALMNAMEN1KMT2A | |
| SCHEMBL29360681 | 0.91 | TSHR (0.41) | TSHRGAALMNAMEN1KMT2A | |
| SCHEMBL18112850 | 0.91 | TSHR (0.41) | TSHRGAALMNAMEN1KMT2A | |
| SCHEMBL29362405 | 0.90 | TSHR (0.40) | TSHRGAALMNAMEN1KMT2A | |
| SCHEMBL18112836 | 0.90 | TSHR (0.40) | TSHRGAALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170208808-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-27 | — | — | US | disclosed |
| EP-2464630-B1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-05-25 | — | — | EP | disclosed |
| US-20130144064-A1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA CROP PROTECTION, LLC (US) | 2013-06-06 | — | — | US | disclosed |
| US-8367844-B2 | Microbiocidal heterocycles | SYNGENTA CROP PROTECTION LLC (US) | 2013-02-05 | — | — | US | disclosed |
| US-20120142698-A1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170208808-A1 | FUNGICIDAL COMPOSITIONS | CYP51A1, CBR3, PPM1F | TSHR 2248/4885GAA 652/4885LMNA 2280/4885 |
| US-20120142698-A1 | MICROBIOCIDAL HETEROCYCLES | CBR1, NOX1, CBR3 | TSHR 800/4885GAA 3965/4885LMNA 3114/4885 |
| US-20130144064-A1 | MICROBIOCIDAL HETEROCYCLES | CBR1, NOX1, CX3CR1 | TSHR 750/4885GAA 4083/4885LMNA 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.