Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9111090 | 1.00 | CXCR4 (0.47) | CXCR4SIGMAR1POLBSMN1; SMN2CHRM2 | |
| SCHEMBL9113900 | 0.88 | POLB (0.42) | CXCR4SIGMAR1POLBSMN1; SMN2CHRM2 | |
| SCHEMBL9113910 | 0.88 | POLB (0.42) | CXCR4SIGMAR1POLBSMN1; SMN2CHRM2 | |
| SCHEMBL9111689 | 0.81 | HRH3 (0.48) | CXCR4SIGMAR1SMN1; SMN2HRH3CYP1A2 | |
| SCHEMBL9111692 | 0.81 | HRH3 (0.48) | CXCR4SIGMAR1SMN1; SMN2HRH3CYP1A2 | |
| SCHEMBL27412019 | 0.79 | CXCR4 (0.50) | CXCR4SIGMAR1POLBSMN1; SMN2CHRM2 | |
| SCHEMBL18995417 | 0.76 | CXCR4 (0.46) | CXCR4SIGMAR1POLBSMN1; SMN2CHRM2 | |
| SCHEMBL947587 | 0.75 | CXCR4 (0.50) | CXCR4SIGMAR1POLBSMN1; SMN2CHRM2 | |
| SCHEMBL8614873 | 0.75 | CXCR4 (0.70) | CXCR4SIGMAR1POLBSMN1; SMN2CHRM2 | |
| SCHEMBL993010 | 0.75 | CXCR4 (0.73) | CXCR4SIGMAR1POLBSMN1; SMN2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |