Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.63 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | THRA | P10827 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 3/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.56 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.56 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.56 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.56 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.56 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.56 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.56 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25269210 | 0.94 | ENPP2 (0.69) | ENPP2DGAT2HPGDPOLBTHRA | |
| SCHEMBL27909135 | 0.94 | ENPP2 (0.69) | ENPP2DGAT2HPGDPOLBTHRA | |
| SCHEMBL27663784 | 0.93 | HPGD (0.67) | ENPP2DGAT2HPGDPOLBTHRA | |
| SCHEMBL7201038 | 0.89 | PSMB11 (0.71) | ENPP2DGAT2HPGDPOLBTHRA | |
| SCHEMBL8499453 | 0.88 | ENPP2 (0.66) | ENPP2DGAT2HPGDPOLBTHRA | |
| SCHEMBL26553751 | 0.87 | ENPP2 (0.61) | ENPP2DGAT2HPGDPOLBTHRA | |
| SCHEMBL26553753 | 0.87 | ENPP2 (0.61) | ENPP2DGAT2HPGDPOLBTHRA | |
| Hydrochloric Acid SCHEMBL25402978 | 0.86 | ENPP2 (0.60) | ENPP2DGAT2HPGDPOLBTHRA | |
| Hydrochloric Acid SCHEMBL25399235 | 0.86 | ENPP2 (0.60) | ENPP2DGAT2HPGDPOLBTHRA | |
| SCHEMBL21998748 | 0.86 | S1PR1 (0.64) | ENPP2DGAT2HPGDPOLBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |