Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL294992 | 0.84 | POLB (0.55) | L3MBTL1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL8484573 | 0.82 | L3MBTL1 (0.52) | L3MBTL1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL8484571 | 0.82 | L3MBTL1 (0.52) | L3MBTL1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL6445918 | 0.82 | L3MBTL1 (0.44) | L3MBTL1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL3988865 | 0.81 | L3MBTL1 (0.50) | L3MBTL1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL22651305 | 0.81 | L3MBTL1 (0.50) | L3MBTL1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL19261358 | 0.81 | MEN1 (0.50) | L3MBTL1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL8488559 | 0.79 | L3MBTL1 (0.48) | L3MBTL1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL19574096 | 0.79 | SMN1; SMN2 (0.49) | L3MBTL1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL8488560 | 0.79 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |