Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 7/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | S100A4 | P26447 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9114907 | 0.80 | HTR2C (0.38) | FADS1HTR2CTRPA1DRD1CNR2 | |
| SCHEMBL9111924 | 0.77 | HTR2C (0.36) | FADS1HTR2CTRPA1DRD1CNR2 | |
| SCHEMBL9111988 | 0.75 | S100A4 (0.52) | S100A4 | |
| SCHEMBL9111982 | 0.75 | S100A4 (0.52) | S100A4 | |
| SCHEMBL9110040 | 0.75 | HTR2C (0.36) | FADS1HTR2CTRPA1DRD1CNR2 | |
| SCHEMBL9240107 | 0.74 | HTR2C (0.35) | FADS1HTR2CTRPA1DRD1CNR2 | |
| SCHEMBL9111781 | 0.73 | HTR2C (0.36) | FADS1HTR2CTRPA1DRD1CNR2 | |
| SCHEMBL9109490 | 0.72 | HTR2C (0.36) | FADS1HTR2CTRPA1DRD1HTR2A | |
| SCHEMBL9113177 | 0.72 | HTR2C (0.33) | FADS1HTR2CTRPA1DRD1KCNA3 | |
| SCHEMBL9113418 | 0.72 | HTR2C (0.33) | FADS1HTR2CTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |