Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112156 | 1.00 | APP (0.36) | APPALDH1A1HSD17B3 | |
| SCHEMBL2094663 | 0.75 | HSD17B3 (0.57) | ALDH1A1HSD17B3 | |
| SCHEMBL2094660 | 0.75 | HSD17B3 (0.57) | ALDH1A1HSD17B3 | |
| SCHEMBL2981659 | 0.74 | APP (0.38) | APPALDH1A1HSD17B3 | |
| SCHEMBL16960755 | 0.72 | APP (0.41) | APPALDH1A1HSD17B3 | |
| SCHEMBL73245 | 0.72 | CYP2C19 (0.46) | ALDH1A1 | |
| SCHEMBL73246 | 0.72 | CYP2C19 (0.46) | ALDH1A1 | |
| SCHEMBL15145957 | 0.72 | APP (0.41) | APPALDH1A1HSD17B3 | |
| SCHEMBL353448 | 0.71 | ALDH1A1 (0.42) | APPALDH1A1 | |
| SCHEMBL5255139 | 0.69 | ALDH1A1 (0.36) | APPALDH1A1HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |