Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | LAP3 | P28838 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30272145 | 1.00 | SPHK1 (0.56) | SPHK1OPRM1TP53CYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL30688481 | 0.98 | SPHK1 (0.54) | SPHK1OPRM1TP53CYP2D6LMNA | |
| SCHEMBL24107252 | 0.98 | OPRM1 (0.56) | SPHK1OPRM1TP53CYP2D6LMNA | |
| SCHEMBL2328466 | 0.95 | SPHK1 (0.60) | SPHK1OPRM1TP53CYP2D6LMNA | |
| SCHEMBL21217006 | 0.95 | SPHK1 (0.60) | SPHK1OPRM1TP53CYP2D6LMNA | |
| SCHEMBL25831975 | 0.95 | SPHK1 (0.60) | SPHK1OPRM1TP53CYP2D6LMNA | |
| SCHEMBL2332779 | 0.95 | SPHK1 (0.60) | SPHK1OPRM1TP53CYP2D6LMNA | |
| SCHEMBL2338645 | 0.95 | SPHK1 (0.60) | SPHK1OPRM1TP53CYP2D6LMNA | |
| SCHEMBL12728004 | 0.95 | SPHK1 (0.60) | SPHK1OPRM1TP53CYP2D6LMNA | |
| SCHEMBL19441327 | 0.95 | SPHK1 (0.60) | SPHK1OPRM1TP53CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647216-A4 | INHIBITION OF THE FORMATION OF NITROSAMINES. | — | 1995-05-17 | — | — | EP | disclosed |
| EP-0647216-A1 | INHIBITION OF THE FORMATION OF NITROSAMINES | SOLVAY INTEROX (US) | 1995-04-12 | — | — | EP | disclosed |
| US-5324857-A | Adding free radical scavenger comprising phenol, aromatic polyol, thiol, or disulfide and chelating agent | SOLVAY INTEROX (US) | 1994-06-28 | — | — | US | disclosed |
| WO-1993022273-A1 | INHIBITION OF THE FORMATION OF NITROSAMINES | SOLVAY INTEROX (US) | 1993-11-11 | — | — | WO | disclosed |
| EP-0409043-B1 | REDUCTION OF NITROSAMINE FORMATION | SOLVAY INTEROX (US) | 1993-01-27 | — | — | EP | disclosed |
| US-5023376-A | Using alkyleneaminopoly(methylene phosphonic acid) compounds | INTEROX AMERICA (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0424965-A1 | Amine oxide process | ETHYL CORPORATION (US) | 1991-05-02 | — | — | EP | disclosed |
| EP-0409043-A1 | Reduction of nitrosamine formation | SOLVAY INTEROX (US) | 1991-01-23 | — | — | EP | disclosed |
| US-4960934-A | Amine oxide process | ETHYL CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
| US-4942260-A | REACTION OF A TERT-AMINE WITH HYDROGEN PEROXIDE IN THE PRESENCE OF CATALYTIC CARBON DIOXIDE | ETHYL CORPORATION (US) | 1990-07-17 | — | — | US | disclosed |
| EP-0356918-A1 | Amine oxide process | ETHYL CORPORATION (US) | 1990-03-07 | — | — | EP | disclosed |
| US-4889954-A | DIALKYLCARBONATE CATALYST | ETHYL CORPORATION (US) | 1989-12-26 | — | — | US | disclosed |
| EP-0307184-A2 | Preparation of Amine Oxides | ETHYL CORPORATION (US) | 1989-03-15 | — | — | EP | disclosed |