Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112203 | 1.00 | SIGMAR1 (0.41) | SIGMAR1HRH3LTA4HCHRNB2CHRNB4 | |
| SCHEMBL9111540 | 0.98 | SIGMAR1 (0.38) | SIGMAR1HRH3LTA4H | |
| SCHEMBL9111537 | 0.98 | SIGMAR1 (0.38) | SIGMAR1HRH3LTA4H | |
| SCHEMBL3199732 | 0.83 | SMN1; SMN2 (0.37) | SIGMAR1HRH3LTA4HCHRNB2CHRNB4 | |
| SCHEMBL3199726 | 0.83 | SMN1; SMN2 (0.37) | SIGMAR1HRH3LTA4HCHRNB2CHRNB4 | |
| SCHEMBL19837632 | 0.81 | SMN1; SMN2 (0.35) | SIGMAR1HRH3LTA4HCHRNB2CHRNB4 | |
| SCHEMBL27961063 | 0.81 | SMN1; SMN2 (0.35) | SIGMAR1HRH3LTA4HCHRNB2CHRNB4 | |
| SCHEMBL4962729 | 0.80 | — | — | |
| SCHEMBL446258 | 0.80 | — | — | |
| SCHEMBL22972376 | 0.79 | SIGMAR1 (0.38) | SIGMAR1HRH3LTA4HCHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |