Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 2/20 | 0.56 |
| ▸ | BACE1 | P56817 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112220 | 1.00 | ALDH1A1 (0.59) | ALDH1A1NR4A1NR4A2NR4A3FFAR1 | |
| SCHEMBL27622370 | 0.87 | PTGER3 (0.65) | ALDH1A1FFAR1FFAR4GSK3BBACE1 | |
| SCHEMBL6176435 | 0.85 | NPC1 (0.55) | ALDH1A1NR4A1NR4A2NR4A3FFAR1 | |
| SCHEMBL6176427 | 0.85 | NPC1 (0.55) | ALDH1A1NR4A1NR4A2NR4A3FFAR1 | |
| SCHEMBL15671252 | 0.83 | NR1H4 (0.56) | ALDH1A1NR4A1NR4A2NR4A3FFAR1 | |
| SCHEMBL15671249 | 0.83 | NR1H4 (0.56) | ALDH1A1NR4A1NR4A2NR4A3FFAR1 | |
| SCHEMBL1233515 | 0.83 | MAOB (0.61) | ALDH1A1LMNACYP2C19HDAC6MAOB | |
| SCHEMBL2280548 | 0.83 | MAOB (0.61) | ALDH1A1LMNACYP2C19HDAC6MAOB | |
| SCHEMBL2555173 | 0.83 | MAOB (0.61) | ALDH1A1LMNACYP2C19HDAC6MAOB | |
| SCHEMBL11021258 | 0.82 | FFAR1 (0.53) | ALDH1A1FFAR1FFAR4PARP10SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460810-B1 | NOVEL FLAVANONE DERIVATIVE | UNIV OKAYAMA NAT UNIV CORP (JP) | 2015-07-15 | — | — | EP | disclosed |
| US-8916526-B2 | Flavanone derivative | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2014-12-23 | — | — | US | disclosed |
| US-20120202980-A1 | Novel Flavanone Derivative | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2012-08-09 | — | — | US | disclosed |
| EP-2460810-A1 | NOVEL FLAVANONE DERIVATIVE | National University Corporation Okayama University (JP) | 2012-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202980-A1 | Novel Flavanone Derivative | GALE, VRK1, GALK1 | ALDH1A1 817/4885NR4A1 1103/4885NR4A2 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.