Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 12/20 | 0.59 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4283052 | 0.86 | APP (0.79) | APPAHRHDAC6HDAC3HDAC1 | |
| SCHEMBL4805108 | 0.80 | AHR (0.71) | APPAHRHDAC6SULT1A1KDM4E | |
| SCHEMBL2136362 | 0.76 | SMN1; SMN2 (0.71) | APPHDAC6SULT1A1KDM4ENPC1 | |
| SCHEMBL10045309 | 0.75 | HDAC3 (0.58) | APPAHRHDAC6HDAC3HDAC1 | |
| SCHEMBL13806234 | 0.75 | APP (0.77) | APPAHRHDAC6HDAC3HDAC1 | |
| SCHEMBL19148568 | 0.75 | MAPT (0.81) | APPAHRHDAC6HDAC3HDAC1 | |
| SCHEMBL10706363 | 0.75 | APP (0.68) | APPAHRHDAC6HDAC3HDAC1 | |
| SCHEMBL1572680 | 0.74 | APP (1.00) | APPSULT1A1GAA | |
| SCHEMBL13806279 | 0.74 | APP (1.00) | APPSULT1A1GAA | |
| SCHEMBL12639217 | 0.73 | SMN1; SMN2 (0.71) | APPAHRHDAC6SULT1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623115-A4 | NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS. | DOW CHEMICAL CO (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0623115-A1 | NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014071-A1 | NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1993-07-22 | — | — | WO | disclosed |
| US-5216110-A | Monomers useful in nucleophilic displacement synthesis of polybenzazole polymers | THE DOW CHEMICAL COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| US-5194562-A | Nucleophilic displacement method for synthesis of non-rigid PBZ polymers | THE DOW CHEMICAL COMPANY (US) | 1993-03-16 | — | — | US | disclosed |
| US-5104960-A | Nucleophilic displacement method for synthesis of non-rigid PBZ polymers | THE DOW CHEMICAL COMPANY (US) | 1992-04-14 | — | — | US | disclosed |