Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 11/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1572680 | 1.00 | APP (1.00) | APPGLAGAASULT1A1 | |
| SCHEMBL1982614 | 0.92 | APP (0.85) | APPGLAGAASULT1A1 | |
| SCHEMBL1982612 | 0.92 | APP (0.85) | APPGLAGAASULT1A1 | |
| SCHEMBL5429982 | 0.91 | APP (0.83) | APPGLAGAASULT1A1 | |
| SCHEMBL4283052 | 0.88 | APP (0.79) | APPGLAGAASULT1A1 | |
| SCHEMBL26017584 | 0.87 | APP (0.76) | APPGLAGAASULT1A1 | |
| SCHEMBL13806242 | 0.86 | APP (0.75) | APPGLAGAASULT1A1 | |
| SCHEMBL23766560 | 0.85 | APP (0.74) | APPGLAGAASULT1A1 | |
| SCHEMBL21752042 | 0.85 | APP (0.74) | APPGLAGAASULT1A1 | |
| SCHEMBL4801119 | 0.85 | SULT1A1 (0.84) | APPGLAGAASULT1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090142269-A1 | ISOTOYPICALLY-LABELED BENZOTHIAZOLE COMPOUNDS AS IMAGING AGENTS FOR AMYLOIDOGENIC PROTEINS | UNIVERSITY OF OITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090142269-A1 | ISOTOYPICALLY-LABELED BENZOTHIAZOLE COMPOUNDS AS IMAGING AGENTS FOR AMYLOIDOGENIC PROTEINS | MAPT, TSPO, APP | APP 3/4885GLA 1082/4885GAA 1207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.