Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | F3 | P13726 | 3/20 | 0.75 |
| ▸ | MEN1 | O00255 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | RAB9A | P51151 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | P4HB | P07237 | 1/20 | 0.75 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.75 |
| ▸ | XDH | P47989 | 1/20 | 0.75 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.71 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | ABL1 | P00519 | 1/20 | 0.63 |
| ▸ | TTR | P02766 | 1/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112457 | 1.00 | MAPT (0.75) | MAPTF3MEN1KMT2ARAB9A | |
| SCHEMBL25219562 | 0.87 | MAOB (0.84) | MAPTF3MEN1KMT2ARAB9A | |
| SCHEMBL25190646 | 0.87 | MAOB (0.84) | MAPTF3MEN1KMT2ARAB9A | |
| SCHEMBL8987059 | 0.86 | BCHE (0.78) | MAPTF3MEN1KMT2ARAB9A | |
| SCHEMBL8987057 | 0.86 | BCHE (0.78) | MAPTF3MEN1KMT2ARAB9A | |
| SCHEMBL25189143 | 0.86 | MAPT (1.00) | MAPTF3MEN1KMT2ARAB9A | |
| SCHEMBL25194802 | 0.86 | MAPT (1.00) | MAPTF3MEN1KMT2ARAB9A | |
| SCHEMBL3889363 | 0.86 | MAPT (1.00) | MAPTF3MEN1KMT2ARAB9A | |
| SCHEMBL145787 | 0.86 | MAPT (1.00) | MAPTF3MEN1KMT2ARAB9A | |
| SCHEMBL3889361 | 0.86 | MAPT (1.00) | MAPTF3MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | disclosed |