Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.39 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9111068 | 1.00 | EGFR (0.43) | EGFRCSNK1ESPHK1SPHK2TDP1 | |
| SCHEMBL9111051 | 0.94 | SPHK1 (0.42) | EGFRSPHK1SPHK2LMNAHDAC3 | |
| SCHEMBL27642615 | 0.83 | EGFR (0.47) | EGFRCSNK1ETDP1ALDH1A1LMNA | |
| SCHEMBL21716147 | 0.81 | EGFR (0.47) | EGFRCSNK1ESPHK1SPHK2TDP1 | |
| SCHEMBL301113 | 0.81 | TRPA1 (0.47) | EGFRCSNK1ETDP1ALDH1A1LMNA | |
| SCHEMBL2787091 | 0.81 | EGFR (0.44) | EGFRCSNK1ETDP1ALDH1A1LMNA | |
| SCHEMBL160811 | 0.81 | TRPA1 (0.47) | EGFRCSNK1ETDP1ALDH1A1LMNA | |
| SCHEMBL9955051 | 0.81 | EGFR (0.44) | EGFRCSNK1ETDP1ALDH1A1LMNA | |
| SCHEMBL4262233 | 0.81 | EGFR (0.44) | EGFRCSNK1ETDP1ALDH1A1LMNA | |
| SCHEMBL4264101 | 0.81 | EGFR (0.44) | EGFRCSNK1ETDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995014383-A1 | ALKYL-N-PYRROLES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-06-01 | — | — | WO | disclosed |