Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112822 | 1.00 | SIGMAR1 (0.38) | SIGMAR1LTA4HHRH3CHRNB2CHRNB4 | |
| SCHEMBL9114626 | 0.98 | SIGMAR1 (0.36) | SIGMAR1LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9114613 | 0.98 | SIGMAR1 (0.36) | SIGMAR1LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL23872301 | 0.79 | HRH3 (0.43) | SIGMAR1LTA4HHRH3CHRNB2CHRNB4 | |
| SCHEMBL7227482 | 0.79 | HRH3 (0.43) | SIGMAR1LTA4HHRH3CHRNB2CHRNB4 | |
| SCHEMBL10748748 | 0.79 | HRH3 (0.43) | SIGMAR1LTA4HHRH3CHRNB2CHRNB4 | |
| SCHEMBL9112160 | 0.77 | HRH3 (0.41) | SIGMAR1HRH3SMN1; SMN2CARM1PRMT6 | |
| SCHEMBL9112244 | 0.77 | POLB (0.33) | SIGMAR1SMN1; SMN2 | |
| SCHEMBL9112154 | 0.77 | HRH3 (0.41) | SIGMAR1HRH3SMN1; SMN2CARM1PRMT6 | |
| SCHEMBL22972376 | 0.76 | SIGMAR1 (0.38) | SIGMAR1LTA4HHRH3CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |