Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | BCHE | P06276 | 5/20 | 0.57 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115182 | 0.97 | ABCG2 (0.70) | ABCG2MAPTLMNAKDM4ECYP1A1 | |
| SCHEMBL9113614 | 0.93 | MAPT (0.70) | ABCG2MAPTLMNAKDM4ECYP1A1 | |
| SCHEMBL9115761 | 0.89 | ABCG2 (0.59) | ABCG2MAPTLMNAKDM4ECYP1A1 | |
| SCHEMBL9114283 | 0.89 | ABCG2 (0.59) | ABCG2MAPTLMNAKDM4ECYP1A1 | |
| SCHEMBL9113047 | 0.88 | KDM4E (0.82) | ABCG2MAPTLMNAKDM4ECYP1A1 | |
| SCHEMBL9113057 | 0.88 | KDM4E (0.82) | ABCG2MAPTLMNAKDM4ECYP1A1 | |
| SCHEMBL9112434 | 0.88 | ABCG2 (0.64) | ABCG2MAPTLMNAKDM4ECYP1A1 | |
| SCHEMBL8148755 | 0.86 | MAPT (0.78) | ABCG2MAPTLMNAKDM4ECYP1A1 | |
| SCHEMBL8148751 | 0.86 | MAPT (0.78) | ABCG2MAPTLMNAKDM4ECYP1A1 | |
| SCHEMBL9110965 | 0.86 | ABCG2 (0.61) | ABCG2MAPTLMNAKDM4ECYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | disclosed |