Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.64 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 4/20 | 0.53 |
| ▸ | IDH1 | O75874 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9113144 | 1.00 | PTPN1 (0.64) | PTPN1CAPN1CTSLCTSBTDP1 | |
| SCHEMBL9112327 | 0.93 | PTPN1 (0.65) | PTPN1ABCG2MAOBTNFRSF1ADPP4 | |
| SCHEMBL9112321 | 0.93 | PTPN1 (0.65) | PTPN1ABCG2MAOBTNFRSF1ADPP4 | |
| SCHEMBL9111964 | 0.88 | PTPN1 (0.67) | PTPN1ABCG2MAOBTNFRSF1ADPP4 | |
| SCHEMBL9114536 | 0.88 | PTPN1 (0.67) | PTPN1ABCG2TNFRSF1A | |
| SCHEMBL9114538 | 0.88 | PTPN1 (0.67) | PTPN1ABCG2TNFRSF1A | |
| SCHEMBL9111958 | 0.88 | PTPN1 (0.67) | PTPN1ABCG2MAOBTNFRSF1ADPP4 | |
| SCHEMBL9112313 | 0.86 | DPP4 (0.58) | PTPN1ABCG2TNFRSF1ADPP4 | |
| SCHEMBL9112315 | 0.86 | DPP4 (0.58) | PTPN1ABCG2TNFRSF1ADPP4 | |
| SCHEMBL9113780 | 0.85 | CTSL (0.58) | PTPN1CAPN1CTSLCTSBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | disclosed |