Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SOD3 | P08294 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720533 | 0.91 | — | — | |
| SCHEMBL55508 | 0.87 | CXCR4 (0.61) | CXCR4HRH3SIGMAR1GNAO1GNAI3 | |
| SCHEMBL1282474 | 0.85 | CXCR4 (0.57) | CXCR4HRH3SIGMAR1GNAO1GNAI3 | |
| SCHEMBL1289987 | 0.82 | — | — | |
| SCHEMBL11122184 | 0.79 | GNAO1 (0.51) | CXCR4SIGMAR1GNAO1GNAI3GNAI1 | |
| SCHEMBL15232418 | 0.79 | GNAO1 (0.51) | CXCR4SIGMAR1GNAO1GNAI3GNAI1 | |
| SCHEMBL10633517 | 0.79 | GNAO1 (0.51) | CXCR4SIGMAR1GNAO1GNAI3GNAI1 | |
| SCHEMBL1189178 | 0.79 | GNAO1 (0.51) | CXCR4SIGMAR1GNAO1GNAI3GNAI1 | |
| SCHEMBL15743617 | 0.79 | GNAO1 (0.51) | CXCR4SIGMAR1GNAO1GNAI3GNAI1 | |
| SCHEMBL5680204 | 0.79 | GNAO1 (0.51) | CXCR4SIGMAR1GNAO1GNAI3GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |