Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26008959 | 0.91 | MDM4 (0.50) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL31370341 | 0.90 | MDM4 (0.51) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL849963 | 0.90 | MDM4 (0.51) | MDM4TP53MDM2SLC17A5 | |
| SCHEMBL24800805 | 0.89 | MDM4 (0.50) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL5175090 | 0.89 | MDM4 (0.53) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL9081984 | 0.89 | MDM4 (0.53) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL29160941 | 0.88 | MDM4 (0.48) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL29160943 | 0.88 | MDM4 (0.48) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL31369488 | 0.88 | MDM4 (0.49) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL31370129 | 0.88 | MDM4 (0.49) | MDM4TP53MDM2CASP3SLC17A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995008550-A1 | ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1995-03-30 | — | — | WO | disclosed |